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Medicinal Chemistry |
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Whether or not you have internal chemistry resources, MedChem
Partners can help accelerate your discovery and development efforts.
For virtual companies and early-stage start-ups, we can be your
medicinal chemistry department. Our staff is experienced in
interacting with biology, pharmacology, legal/IP and
bioinformatics. We can be your go-to source for medicinal chemistry
expertise and synthesis.
For companies with internal chemistry, we can free up company
resources by preparing advanced intermediates, exploring SAR,
working on back-up compounds, broadening the coverage of chemical
space, or helping solve issues with ADME or physico-chemical
properties. In addition we can assist in the investigation of new
projects or potential leads allowing internal resources to be used
elsewhere until the project is validated.
Our scientists have expertise in all phases of medicinal chemistry
from early stage hit generation to late stage lead optimization. Our
experience ranges from project inception and resource identification
to synthetic route planning and library synthesis. Whether it's
re-synthesis of a hit for validation or exploring the SAR of a lead
compound, we have the experience and resources to accomplish the
task.
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Hit validation and evaluation
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Proof of principle support
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Hit re-synthesis
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Synthesis of reference compounds
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SAR development
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Hit explosion and lead generation
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Lead optimization
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Optimization of ADME
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Synthesis of advanced intermediates
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Metabolite and stable isotope synthesis
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Exploratory chemistry
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Cold route finding in support of radiochemistry
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