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 Our staff has many years
of experience in the drug discovery and development area. We can help in
the earliest planning stages to put your project on a solid foundation.
Whether it’s assessing project or route viability, identifying potential
risks and pitfalls or locating key resources, we can help.
Many of our scientists have managed projects from inception, through
strategic planning and early discovery, and into pre-clinical development.
Our scientists are familiar with potential pitfalls such as IP, PK/Tox, route viability, sourcing for starting materials,
and cost-of-goods. We can help mitigate some of the risk associated with
these issues by identifying them early on and developing a route around
them, or a strategy to deal with them.
At MedChem Partners, we have hands-on experience in designing discovery
programs from the ground up. From planning and initial library selection
to establishing screening criteria and SAR, to fine tuning ADME and
physico-chemical properties, we can help.
R&D Consultation
MedChem Partners provides strategic R&D Consultation in the following
areas:
- Project viability, planning and
management
- Strategic consulting
- Establishment of screening
strategies
- Library selection
- Structure guided drug design
- Hit validation and evaluation
- Risk and viability assessment
- Managing off shore chemistry
resources
Development
At MedChem Partners, our scientists have seen first-hand the potential
pitfalls and road blocks that can occur in the drug development process.
We are familiar with issues such as lack of bioavailability, poor
solubility and inappropriate CYP450 profiles and have experience
addressing them. Development issues are some of the most challenging that
occur in drug R&D. We can help you overcome these challenges by
establishing proper screening regimes in e-ADME and PK, working with
formulations experts and enhancing ADME or physico chemical properties via
chemical modification.
Patent & Chemical Space
We understand that the road to drug discovery is long and difficult.
Often the first step is in the drafting of a grant or proposal. MedChem
Partners can help by providing professional medicinal chemistry
consultation on the drafting of these documents. We have written SBIR
grants and proposals and can assist with the preparation of your grants or
proposals. Whether it’s just a few questions, or a complete draft you
need, we can work with your scientists or managers to put their ideas and
inventions in a format that will facilitate the patenting process.
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